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ALTITUDEAliskiren Trial in Type 2 Diabetes Using Cardiovascular and Renal Disease Endpointswas a study designed to test the benefit of adding aliskiren to a standard therapy of an ACE inhibitor or an angiotensin II receptor blocker in patients with type 2 diabetes mellitus and chronic kidney diseasecardiovascular diseaseor bothThe study was terminated early because of an increased risk of adverse outcomesCardiovascular death and stroke were both numerically more frequent in the aliskiren group than in the placebo group and adverse events and serious adverse events of interesthyperkalaemiahypotension and renal dysfunctionwere more frequently reported in the aliskiren group than in the placebo group.

Take the missed dose as soon as you rememberSkip the missed dose if it is almost time for your next scheduled doseDo not take extra medicine to make up the missed dose.

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The dosage is based on your medical condition and response to treatmentFor childrenthe dosage is also based on weight.

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