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Labetalol HCl combines both selectivecompetitivealpha 1adrenergic blocking and nonselectivecompetitivebeta-adrenergic blocking activity in a single substanceIn manthe ratios of alphato beta-blockade have been estimated to be approximately 1:3 and 1:7 following oral and intravenousIVadministrationrespectivelyBeta 2agonist activity has been demonstrated in animals with minimal beta 1agonistISAactivity detectedIn animalsat doses greater than those required for alphaor beta-adrenergic blockadea membrane stabilizing effect has been demonstrated.
This medication is both an alpha blocker and beta blockerIt works by blocking the action of certain natural chemicals in your body such as epinephrine on the heart and blood vesselsThis effect lowers the heart rateblood pressureand strain on the heart.
This drug may make you dizzyAlcohol or marijuana can make you more dizzyDo not driveuse machineryor do anything that needs alertness until you can do it safelyLimit alcoholic beveragesTalk to your doctor if you are using marijuana.
The antianginal efficacy of labetalol HCl has not been studiedIn 37 patients with hypertension and coronary artery diseaselabetalol HCl did not increase the incidence or severity of angina attacks.
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