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Rhea isoniazid – frequently asked questions. Buy Isoniazid online Information about Isoniazid. Tell your doctor and pharmacist if you are allergic to isoniazidany other medicationsor any of the ingredients in isoniazid tablets or oral solutionAsk your pharmacist for a list of the ingredientstell your doctor and pharmacist what other prescription and nonprescription medicationsvitaminsnutritional supplementsand herbal … להמשיך לקרוא Isoniazid and rifampin cost

Rhea isoniazid – frequently asked questions.

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Tell your doctor and pharmacist if you are allergic to isoniazidany other medicationsor any of the ingredients in isoniazid tablets or oral solutionAsk your pharmacist for a list of the ingredientstell your doctor and pharmacist what other prescription and nonprescription medicationsvitaminsnutritional supplementsand herbal products you are taking or plan to takeBe sure to mention any of the followingacetaminophenTylenolantacidscarbamazepineCarbatrolEquetroTegretolotherscitalopramCelexaescitalopramLexaprofluoxetineProzacSarafemSymbyaxfluvoxamineLuvoxketoconazoleNizoralparoxetinePaxilphenytoinDilantinPhenyteksertralineZolofttheophyllineElixophyllinTheochronTheo-24and valproic acidDepakeneDepakoteMany other medications may interact with isoniazidso be sure to tell your doctor about all the medications you are takingeven those that do not appear on this listYour doctor may need to change the doses of your medications or monitor you carefully for side effectsin addition to the conditions listed in the IMPORTANT WARNING sectiontell your doctor if you have or have ever had kidney diseasediabetestinglingburningand pain in the fingers or toesperipheral neuropathyor human immunodeficiency virusHIVtell your doctor if you are pregnant or plan to become pregnantIf you become pregnant while taking isoniazidcall your doctoryou should know that you should not drink alcohol while taking this drug.

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Isoniazid is a prodrug and must be activated by bacterial catalaseSpecficiallyactivation is associated with reduction of the mycobacterial ferric KatG catalase-peroxidase by hydrazine and reaction with oxygen to form an oxyferrous enzyme complexOnce activatedisoniazid inhibits the synthesis of mycoloic acidsan essential component of the bacterial cell wallAt therapeutic levels isoniazid is bacteriocidal against actively growing intracellular and extracellular Mycobacterium tuberculosis organismsSpecifically isoniazid inhibits InhAthe enoyl reductase from Mycobacterium tuberculosisby forming a covalent adduct with the NAD cofactorIt is the INH-NAD adduct that acts as a slowtight-binding competitive inhibitor of InhA.

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